brewer's yeast improves blood pressure in type 2 diabetes mellitus.

this study was conducted to investigate the effects of brewer's yeast supplementation on serum lipoproteins and blood pressure in patients with type 2 diabetes mellitus.in a randomized double blind clinical trial, 90 adults with type 2 diabetes mellitus were recruited, and divided randomly into 2 groups, trial group received brewer's yeast (1800 mg/day) and control group received placebo for 12 weeks. weight, bmi, food consumption (based on 24 hour food recall), fasting serum lipoproteins (cholesterol, triglyceride, ldl-c, hdl-c), systolic and diastolic blood pressures were measured before and after the intervention. data analyses were performed by statistical package for social sciences ver. 18.0, and the statistical tests included independent t-test, paired t-test, kolmogorov-smirnov and analysis of covariance. this trial was registered in iranian registry of clinical trials (irct), no.irct138807062513n1.eighty-four subjects (21 men and 63 women) aged 46.3±6.1 years completed the study. after 12 weeks supplementation, systolic and diastolic blood pressures were decreased in the group receiving brewer's yeast (4.1±1.5, p=0.007 and 5.7±0.6, p=0.001 respectively). no-significant changes in ldl-c, hdl-c, triglyceride and cholesterol were shown.supplementation with brewer's yeast besides the usual treatment of type 2 diabetes mellitus can reduce systolic and diastolic blood pressures in diabetic patients.